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In contrast to the PCOS group, the ovarian tissue showed well-developed antral follicles in the genistein-treated rats including substantial reductions in total populations of ovarian atretic follicles, normal granulosa cell layer, a defined theca layer, and few corpus lutea (Figure 3D)
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For instance, vitamin B2 (riboflavin) and the essential trace mineral selenium are necessary for the recycling [the enzyme glutathione reductase is considered a “flavoenzyme” (i.e., it needs a coenzyme form of riboflavin, flavin adenine dinucleotide to operate)] of and use [the enzyme glutathione peroxidase is a “selenoprotein” (i.e., it needs its cofactor selenium to operate)] of glutathione, respectively