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Keywords: Peyronie’s disease, Duplex Doppler ultrasound, Tunical plication, Plaque incision and grafting, Intralesional therapy, Oral Peyronie’s disease therapy, Dupuytren’s disease, Ledderhose disease, Genetics INTRODUCTION Peyronie’s Disease (PD) is a superficial fibrosing condition of the penis characterized by the presence of fibrotic plaques often leading to penile deformity, with or without concomitant pain